http://tigcc.ticalc.org/doc/comopts.html#SEC10
-Winline --param inline-unit-growth=10000 --param large-function-growth=10000 --param max-inline-insns-single=100000m2.450s 40000000 'self' message sends with --param options
0m2.650s 40000000 'self' message sends without options
That's a 7.5% boost. While the binary is now twice as large, in my case the binary is still small - 100K stripped.